The effect of beta-adrenergic receptor blocking drugs on cerebral blood flow.
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چکیده
منابع مشابه
Effect of Beta-Adrenergic Blockade With Propranolol on Cerebral Blood Flow, Autoregulation
Cerebral autoregulation and vasomotor responsiveness to carbon dioxide were measured quantitatively in normal baboons before and after intravertebral or intravenous infusion of the beta-adrenergic blocking agent, propranolol hydrochloride (Inderal®). Continuous measurements were made of cerebral blood flow (CBF: measured as bilateral internal jugular venous outflow using an electromagnetic flow...
متن کاملEffect of beta-adrenergic blockade with propranolol on cerebral blood flow, autoregulation and CO2 responsiveness.
Cerebral autoregulation and vasomotor responsiveness to carbon dioxide were measured quantitatively in normal baboons and after intravertebral or intravenous of the beta-adrenergic blocking agent, propranolol hydrochloride (Inderal). Continuous measurements were made of cerebral blood flow (CBF: measured as bilateral internal jugular venous outflow using an electromagnetic flowmeter), cerebral ...
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The reduction in blood pressure seen with the use of beta-blocking drugs was an unexpected finding. Initially there was resistance to their use as the reduction of cardiac output and increase in peripheral resistance from beta-blockade was considered an undesirable pharmacological action for a drug in the treatment of hypertension. However, beta-blockers have now become established in the treat...
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The effect of propranolol was studied on 23 dental phobics in a double-blind, placebo-controlled clinical trial involving actual dental treatment. The subjects were selected because they showed high physiological reactivity in the dental situation. Twelve subjects received the test drug and 11 subjects received the placebo at individualized doses of either 80 or 120 mg. A significant difference...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1979
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1979.tb00991.x